The Wars of the Diadochi or Wars of Alexander's Successors of 322–272 BC were a series of conflicts fought between the generals of Alexander the Great, known as the Diadochi, over who would rule his empire following his death. The fighting started almost immediately after his death in 323 BC. The crucial battle of Ipsus fought in 301 BC, established Ptolemies and Seleucids as the two major dynasties of the Hellenistic world. The battle of Corupedium in 281 BC, left Seleucus I as the only living successor among the original Diadochi. However, the struggle over Macedon and hegemony over Greece was concluded in favour of the Antigonids only in 272 BC with the death of Pyrrhus of Epirus.