Alexander the Great of Macedon carried out a series of conquests and military campaigns from 336 to 323 BC. They began with his conquest of the Achaemenid Empire, which was ruled by Darius III. After a series of victories over the Persians and the defeat of Darius, he began a campaign against local chieftains and warlords that stretched from Greece to as far as the Indus Valley. At the time of his death, Alexander ruled over most regions of Greece and the conquered Achaemenid Empire, including much of Achaemenid Egypt.